In vivo imaging of extracellular pH using 1H MRSI
نویسندگان
چکیده
منابع مشابه
Mapping extracellular pH in rat brain gliomas in vivo by 1H magnetic resonance spectroscopic imaging: comparison with maps of metabolites.
The value of extracellular pH (pH(e)) in tumors is an important factor in prognosisand choice of therapy. We demonstrate here that pH(e) can be mappedin vivo in a rat brain glioma by (1)H magnetic resonance spectroscopic imaging (SI) of the pH buffer (+/-)2-imidazole-1-yl-3-ethoxycarbonylpropionic acid (IEPA). (1)H SI also allowed us to map metabolites, and, to better understand the determinant...
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 1999
ISSN: 0740-3194,1522-2594
DOI: 10.1002/(sici)1522-2594(199904)41:4<743::aid-mrm13>3.3.co;2-q